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The role of cytochrome P450 polymorphisms in the pharmacokinetics of oral esketamine.
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Coerts DT, Smith-Apeldoorn SY, Oude Nijhuis JC, van Schaik RHN, Tamminga WJ, Touw DJ, Veraart JKE, Schoevers RA, van Dalfsen JH
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42031731
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24-04-2026
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04-05-2026
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Prospective clinical evaluation of cell-free DNA next generation sequencing in patients with suspected metastatic lung cancer.
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Steendam CMJ, Meijers RWJ, Atmodimedjo P, van Dijk L, van der Leest C, van Loenhout KCJ, van 't Westeinde SC, Dumoulin DW, Hanselaar WEJJ, Paats MS, de Jonge E, van Schaik RHN, von der Thüsen JH, Aerts JGJV, Dingemans AC, Dubbink HJ
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41951723
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08-04-2026
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04-05-2026
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Leucine supplementation does not attenuate the decline in daily muscle protein synthesis rates or preserve leg muscle mass during leg immobilization in young or older adults: a double-blind randomized trial.
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Churchward-Venne TA, Pinckaers PJ, Smeets JS, Marzuca-Nassr GN, Gorissen SH, Fuchs CJ, Senden JM, Goessens JP, Gijsen AP, Wodzig WK, van Loon LJ
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41580240
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01-04-2026
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13-04-2026
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Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6 and CYP2C19 and tricyclic antidepressants.
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Kleine Schaars K, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Guchelaar HJ, Houwink EJF, Risselada A, Rongen GAPJM, van Schaik RHN, Swen JJ, Touw D, Deneer VHM, van Westrhenen R
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41526670
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01-03-2026
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04-05-2026
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Interaction of CYP2C19 with the effect of clopidogrel in secondary prevention of major ischemic events: Systematic review and meta-analysis.
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Kremers FC, van den Biggelaar J, Lingsma HF, van Schaik RH, Roozenbeek B, Dippel DW
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40844153
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01-03-2026
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04-05-2026
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Sex differences in outcomes of vitamin K antagonist treatment in patients with a mechanical heart valve: a Dutch population-based cohort study.
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Kempers EK, Visser C, Seelig J, Chen Q, Adriaansen HJ, Beinema MJ, Ten Cate-Hoek AJ, Faber LM, Dronkers CEA, Nierman MC, Schindhelm RK, Wiersma NM, Stork ADM, Klok FA, Leebeek FWG, Pisters R, Cannegieter SC, De Caterina R, Hemels MEW, Ten Cate H, Kavousi M, Kruip MJHA
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41072734
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01-03-2026
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16-04-2026
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Genotype-Guided P2Y(12)-Inhibitor De-Escalation Strategy in Acute Coronary Syndrome: Observational Evidence From the POPular-GUIDE PCI.
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van den Broek WWA, Azzahhafi J, van de Pol QYF, Chan Pin Yin DRPP, van der Sangen NMR, Sivanesan S, Peper J, Harmsze AM, Walhout RJ, Tjon Joe Gin M, Breet NJ, Langerveld J, Appelman Y, van Schaik RHN, Henriques JPS, Kikkert WJ, Ten Berg JM
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41744086
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26-02-2026
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04-05-2026
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Survival of patients with colorectal or pancreatic cancer who received UGT1A1 genotype-guided dosing of irinotecan in the Netherlands (2017-2024): a retrospective, multicentre cohort study.
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Peeters SLJ, Heersche N, Böhm D, Böhringer S, Guiljam R, Hulshof EC, de Man FM, de With M, Joosse M, Oomens G, Wu QY, Osman A, Bins S, van Hellemond IEG, Haberkorn BCM, Verschoor AJ, Wumkes ML, van Schaik RHN, Thijs AM, Gelderblom H, Guchelaar HJ, Mathijssen RHJ, Deenen MJ
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41777427
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23-02-2026
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04-05-2026
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Global Investigation of Clinical Implementation Strategies for DPYD Testing to Guide Fluoropyrimidine Therapy.
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El Rouby N, Aquilante CL, Bargal SA, Cavallari LH, Duarte JD, Gunderson K, Mazhindu T, Nagy M, Nie X, Nguyen DG, Patel JN, Skaar TC, Smith DM, Tuteja S, van Schaik RHN, Hicks JK, PGRN Implementation Working Group
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41456101
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01-01-2026
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04-05-2026
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Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between TPMT/NUDT15 and thiopurines.
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Coenen MJH, Nijenhuis M, Soree B, de Boer-Veger NJ, Buunk AM, Guchelaar HJ, Houwink EJF, Risselada A, Rongen GAPJM, Swen JJ, Touw DJ, van Westrhenen R, Deneer VHM, van Schaik RHN
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41318725
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01-01-2026
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04-05-2026
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The 8th European Society of Pharmacogenomics and Personalized Therapy (ESPT) congress.
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van Schaik RHN, Swen JJ, Llerena A, Koch BCP, Coenen MJH, Molden E, Mathijssen RHJ, Cecchin E, Wadelius M, van Gelder T, Picard N, Daly AK, Stanković S, van den Broek D, Rodriguez-Antona C, Matic M, Cascorbi I, van der Lee M, Dolzan V, Morris T, Niemi M
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41924848
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01-01-2026
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04-05-2026
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Sex-based differences in biomarker trajectories in acute coronary syndrome patients from the BIOMArCS study.
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Gärtner C, Haaf MET, Akkerhuis KM, Oemrawsingh RM, van Schaik RH, de Rijke YB, Kardys I, Appelman Y, Boersma E
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41372369
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10-12-2025
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04-05-2026
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ATP-binding cassette transporter polymorphisms and the pharmacokinetics of oral esketamine.
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Oude Nijhuis JC, Coerts DT, van Dalfsen JH, Smith-Apeldoorn SY, Veraart JKE, Schoevers RA, Touw DJ, van Schaik RHN, Tamminga WJ
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41560413
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01-12-2025
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04-05-2026
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Machine learning for risk stratification in the emergency department (MARS-ED): a randomized controlled trial.
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van Dam PMEL, van Doorn WPTM, Sevenich L, Lambriks L, Cals JWL, Bekers O, Stassen PM, Meex SJR
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41326390
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01-12-2025
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07-04-2026
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Predicting metabolic preferences through transcriptomics: a data-driven approach to align metabolic signatures with gene expression profiles.
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Lerink LJS, de Winter MJ, Bakker JA, Alwayn IPJ, Ploeg RJ, Mulvey JF, Lindeman JHN
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41189637
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22-10-2025
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09-04-2026
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A Population Pharmacokinetic Model and Dosing Algorithm to Guide the Tacrolimus Starting and Follow-Up Dose in Living and Deceased Donor Kidney Transplant Recipients.
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Francke MI, Sassen SDT, Lloberas N, Colom H, Elens L, Moudio S, de Vries APJ, Moes DJAR, van Schaik RHN, Hesselink DA, de Winter BCM
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40588615
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01-09-2025
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04-05-2026
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Changes in quality of vitamin K antagonist treatment and clinical outcomes during Ramadan: a Dutch population-based cohort study.
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Kempers EK, Chen Q, van Rein N, Atiq F, Schindhelm RK, Wiersma NM, Dronkers CEA, Beinema M, Ten Cate-Hoek AJ, Nierman MC, Stork ADM, Moriarty P, Klok FA, Cannegieter SC, Kruip MJHA
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40988731
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13-08-2025
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16-04-2026
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Semaglutide impairs bioavailability of alectinib: a note of warning based on a cross-over pharmacokinetic drug-drug interaction study.
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Heersche N, Lanser DAC, Oomen-de Hoop E, Içli A, de Bruijn P, Paats MS, van Rossum EFC, Koolen SLW, van Schaik RHN, Dingemans AC, Veerman GDM, Mathijssen RHJ
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40308149
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01-08-2025
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04-05-2026
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Pharmacokinetics of betamethasone in pre-eclampsia: An in vivo and ex vivo study.
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Schoenmakers S, Li L, Kluivers ACM, Broekhuizen M, Harhangi MS, Danser AHJ, Reiss I, Allegaert K, van den Berg SAA, van Zelst BD, van Schaik RHN, DeKoninck PLJ, Ronde E, Sassen SDT, Simons SHP, Koch BCP
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40083164
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01-08-2025
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04-05-2026
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Recommendations for (Pharmaco)Genetic Sampling in Patients Following Allogeneic Hematopoietic Stem Cell Transplantation.
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Bokma A, Matic M, Ralf A, van den Bosch BJC, Kayser M, van Schaik RHN, Lafeber M, Coenen MJH, Atrafi F
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40802525
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01-08-2025
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04-05-2026
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Daily blood flow restriction does not preserve muscle mass and strength during 2 weeks of bed rest.
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Fuchs CJ, Hermans WJH, Nyakayiru J, Weijzen MEG, Smeets JSJ, Aussieker T, Senden JM, Wodzig WKHW, Snijders T, Verdijk LB, van Loon LJC
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38411283
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01-07-2025
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14-04-2026
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Dose-individualisation of fluoropyrimidines based on pre-treatment serum uracil levels: the Alpe2U study.
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Knikman JE, de With M, Heersche N, Lopez-Yurda M, Baars A, Creemers GJ, Droogendijk HJ, Fiets E, Imholz ALT, Iersel LV, Mandigers CMPW, van de Vendel AJ, Jeurissen FJF, Nieboer P, Deenen MJ, van de Poel MHW, Wymenga MNM, van Schaik RHN, van den Bosch BJC, Hoop EO, Rosing H, Swen JJ, Gelderblom H, Schellens JHM, Beijnen JH, Mathijssen RHJ, Guchelaar HJ, Cats A
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40466468
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25-06-2025
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04-05-2026
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Relationship Between Exercise-Induced Cardiac Troponin Elevations and Occult Coronary Atherosclerosis in Middle-Aged Athletes.
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Janssen SLJE, van Everdingen WM, Saalmink WBJ, Lamers SK, Vroemen WHM, Denessen EJS, Berge K, Bekers O, Hopman MTE, Brink M, Habets J, Aengevaeren VL, Mingels AMA, Nijveldt R, Eijsvogels TMH, TREAT study collaboration
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40533126
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24-06-2025
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07-04-2026
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ADRB2 genotype-guided treatment for childhood asthma: Cost analysis of the PUFFIN and PACT trials.
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Slob EMA, Frederix GWJ, Vijverberg SJH, Noij LCE, Ruffles T, Vasbinder EC, Mukhopadhyay S, van Schaik RHN, Kersten ETG, Pijnenburg MW, Koppelman GH, Maitland-van der Zee AH, PUFFIN and PACT investigators
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40464075
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01-06-2025
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04-05-2026
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Cost-effectiveness of implementing a genotype-guided de-escalation strategy in patients with acute coronary syndrome.
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van den Broek WWA, Azzahhafi J, Chan Pin Yin DRPP, van der Sangen NMR, Sivanesan S, Dijksman LM, Walhout RJ, Tjon Joe Gin M, Breet NJ, Langerveld J, Vlachojannis GJ, van Bommel RJ, Appelman Y, van Schaik RHN, Henriques JPS, Kikkert WJ, Ten Berg JM
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39537191
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02-05-2025
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04-05-2026
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