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Project 103	Farmacogenetica en hypertensie (Erasmus MC)
Onderzoekslijn	Farmacogenetica (Erasmus MC)
Omschrijving
Projectleider	Prof. dr. R.H.N.(Ron) van Schaik
Instituut	Erasmus MC Rotterdam
Trefwoorden	Pharmacogenetics, hypertension
Status	Lopend
Periode	8-2006 - 1-2020
Partners
Medewerkers
Financiering	1e Geldstroom - Intern
Publicaties	Cardiac aldosterone in subjects with hypertrophic cardiomyopathy. Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes. Vitamin K epoxide reductase complex subunit 1 (VKORC1) polymorphism and aortic calcification: the Rotterdam Study. Common ATP-binding cassette B1 variants are associated with increased digoxin serum concentration. Genetic variation in the CYP2D6 gene is associated with a lower heart rate and blood pressure in beta-blocker users.